IV Therapy NCLEX Challenge Quiz
Test your advanced knowledge of IV therapy with these analysis-level nursing scenarios.
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Quiz Questions & Answers
Review every prompt, the correct responses, and helpful context to prep for your own run-through.
Question 1: A patient receiving TPN through a central line develops sudden dyspnea, chest pain, and tachycardia. The nurse's first action should be:
Obtain a 12-lead ECG
Stop the TPN infusion immediately
Call for a rapid response team
Check blood glucose levels
Question 2: A nurse is caring for a patient with a peripheral IV who reports burning at the insertion site. Assessment reveals redness and a hard cord extending up the vein. The most likely diagnosis is:
Infiltration
Phlebitis
Extravasation
Local infection
Question 3: When administering multiple IV medications through the same line, which sequence is correct?
Isotonic solutions first, then hypotonic
Compatible medications in order of decreasing pH
Antibiotics first, then other medications
Highest concentration to lowest concentration
Question 4: A patient with sepsis requires rapid fluid resuscitation. Which IV catheter size would be most appropriate?
22 gauge
16 gauge
24 gauge
20 gauge
Question 5: A patient's IV site shows blanching, coolness, and decreased pulse distal to insertion. The nurse should first:
Apply warm compresses
Remove the IV immediately
Slow the infusion rate
Document findings and monitor
Question 6: A patient requires potassium replacement via IV. The maximum safe peripheral concentration is:
40 mEq/L
20 mEq/L
60 mEq/L
10 mEq/L
Question 7: A patient's central line blood return is sluggish. Which intervention should the nurse try first?
Administer tissue plasminogen activator
Reposition the patient
Force flush the line
Replace the central line
Question 8: A patient with a PICC line develops arm swelling and discomfort. The most likely cause is:
Infection
Deep vein thrombosis
Infiltration
Muscle strain