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ALS (Amyotrophic Lateral Sclerosis) NCLEX Practice Questions

Test your knowledge about ALS, its symptoms, management, and nursing interventions through these practice questions.

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Mageto
Published April 11, 2026

Quiz Questions & Answers

Review every prompt, the correct responses, and helpful context to prep for your own run-through.

Question 1: A nurse is assessing a client with suspected Amyotrophic Lateral Sclerosis (ALS). Which clinical manifestation should the nurse expect to find?

Loss of peripheral vision and increased intraocular pressure

Cognitive decline and memory loss

Progressive muscle weakness and atrophy

Resting tremors and shuffling gait

Question 2: A client with ALS is experiencing difficulty swallowing (dysphagia). Which nursing intervention is the priority?

Provide thin liquids to make swallowing easier.

Maintain the client in a supine position during meals.

Assess the client’s lung sounds and oxygen saturation.

Encourage the client to use a straw for all liquids.

Question 3: The nurse is discussing the progression of ALS with a newly diagnosed client. Which statement by the nurse is accurate regarding the disease?

Medication can cure the disease if started in the early stages.

The disease primarily affects your sensory nerves, causing chronic pain.

Your cognitive function and mental alertness will usually remain intact.

Muscle strength typically returns after a period of exacerbation.

Question 4: A client with ALS is prescribed Riluzole. What information should the nurse include when teaching the client about this medication?

You will need frequent blood tests to monitor your liver function.

This drug is a sedative and will help you sleep through muscle cramps.

This medication will reverse the muscle damage already caused.

Stop taking the medication immediately if you develop a cough.

Question 5: Which respiratory assessment finding in a client with ALS requires immediate notification of the healthcare provider?

Clear breath sounds in all lung fields

Increased use of accessory muscles and a weak cough

A respiratory rate of 18 breaths per minute

Oxygen saturation of 96% on room air

Question 6: A client with advanced ALS is being evaluated for a percutaneous endoscopic gastrostomy (PEG) tube. What is the primary purpose of this procedure for this client?

To provide a route for long-term mechanical ventilation

To maintain adequate nutrition and reduce the risk of aspiration

To administer high-dose IV corticosteroids

To prevent the development of pressure ulcers

Question 7: The nurse is helping a client with ALS plan for end-of-life care. Which action should the nurse take first?

Refer the client to a local support group.

Discuss the benefits of a high-calorie diet.

Schedule a physical therapy consultation.

Assist the client in completing an Advanced Directive.

Question 8: A client with ALS reports 'twitching' in the muscles of the arms and legs. How should the nurse document this finding?

Ataxia

Fasciculations

Chorea

Myoclonus

Question 9: When planning care for a client with ALS, which member of the interdisciplinary team should the nurse prioritize for a consultation regarding communication?

Occupational Therapist

Speech-Language Pathologist

Case Manager

Physical Therapist

Question 10: Which statement by a family member of a client with ALS indicates a need for further teaching?

I should prepare a suction machine to have at the bedside.

We should start looking into hospice care options for the future.

My father will eventually lose his ability to feel pain and touch.

We should encourage my father to perform range-of-motion exercises.