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T Cell & B Cell Development Quiz

Test your knowledge about the development, maturation, and activation of T cells and B cells in the immune system.

8 questions
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Shalini
Published March 2, 2026

Quiz Questions & Answers

Review every prompt, the correct responses, and helpful context to prep for your own run-through.

Question 1: Where do T cells complete their maturation process?

Lymph nodes

Spleen

Thymus

Bone marrow

Question 2: What is the primary site of B cell development?

Bone marrow

Tonsils

Liver

Thymus

Question 3: Which process is crucial for both T and B cells to avoid autoimmune responses?

Positive selection

Clonal expansion

Negative selection

Isotope switching

Question 4: What type of cell is essential for activating naive T cells?

B cells

Plasma cells

Antigen-presenting cells

Natural killer cells

Question 5: What happens to B cells after successful activation?

They return to bone marrow

They transform into T cells

They immediately die

They differentiate into plasma cells and memory B cells

Question 6: Which signal is NOT required for T cell activation?

Co-stimulatory signals

Direct contact with B cells

Cytokine signals

TCR recognition of antigen-MHC

Question 7: What is the main function of memory B and T cells?

Immediate antibody production

Producing inflammatory signals

Destroying infected cells

Providing rapid response to repeated infections

Question 8: Which process allows B cells to produce different antibody classes?

Class switching

Receptor editing

Positive selection

Clonal deletion